It can be challenging for people with chronic musculoskeletal pain, such as osteoarthritis or fibromyalgia, to find a medication that works for them. Nonsteroidal anti-inflammatory drugs (NSAIDs) can be effective, but they have limitations. To avoid side effects, it is generally advised to take them only for a short period of time. Acetaminophen (Tylenol®) is not always effective.
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